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Background:

Heavy menstrual bleeding (HMB), a prevalent and distressing condition, is primarily defined by the patient's perception and observable signs like frequent pad or tampon changes, large clots, and disruption of daily activities.

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Women with HMB often experience reduced health-related quality of life, attributed to irritation, inconvenience, associated pain, self-consciousness, and social embarrassment.

Despite its impact, less than half of those with heavy bleeding seek medical assistance, leading to suboptimal care.


Recommendations on diagnostic evaluation of HMB:

  • Perform a complete blood cell count for women reporting HMB, excluding ferritin, thyroid, or hormone testing.
  • Evaluate for coagulation disorders, like von Willebrand disease, in women experiencing HMB since the onset of their periods.
  • Consider pelvic ultrasonography if the uterus is palpable abdominally or if pelvic examination results are inconclusive; transvaginal ultrasonography is preferred for women with significant dysmenorrhea or a bulky, tender uterus.
  • Early outpatient hysteroscopy is recommended during HMB investigations if the patient's history suggests submucosal fibroids, polyps, or endometrial pathology.
  • Focus on interventions that enhance the quality of life rather than fixating on blood loss.
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Recommendations on treatment of HMB:

  • If there is low suspicion of an anatomic abnormality after history and physical examination, contemplate empirical pharmacologic management.
  • For women with fibroids smaller than 3 cm without cavity distortion, other pathology, or suspected adenomyosis, consider the Levonorgestrel-releasing intrauterine system (LNG-IUS) as first-line treatment.
  • In case of LNG-IUS refusal, discuss non-hormonal options such as Tranexamic acid, nonsteroidal anti-inflammatory drugs (NSAIDs), combined hormonal contraception, or cyclical progestin-only medication.

Conclusion:

In conclusion, regular inquiries about menstrual health in primary care can enhance outcomes and patient contentment. These recommendations offer a structure for the assessment and treatment choices for women experiencing HMB and is applicable in outpatient settings.


Reference:

Douglass LA, Davis AM. Assessment and Management of Heavy Menstrual Bleeding. JAMA. 2020;323(3):270-1.

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